Clinical Implications of Circulating Tumor DNA Tumor Mutational Burden (ctDNA TMB) in Non‐Small Cell Lung Cancer

BACKGROUND. Tissue tumor mutational burden (TMB) has emerged as a potential biomarker predicting response to anti‐programmed cell death‐1 protein receptor (PD‐1)/programmed cell death‐1 protein ligand (PD‐L1) therapy, but few studies have explored using circulating tumor DNA (ctDNA) TMB in non‐small...

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Vydáno v:Oncologist
Hlavní autoři: Chae, Young Kwang, Davis, Andrew A., Agte, Sarita, Pan, Alan, Simon, Nicholas I., Iams, Wade T., Cruz, Marcelo R., Tamragouri, Keerthi, Rhee, Kyunghoon, Mohindra, Nisha, Villaflor, Victoria, Park, Wungki, Lopes, Gilberto, Giles, Francis J.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2019
Témata:
Immuno‐Oncology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656496/
https://ncbi.nlm.nih.gov/pubmed/30867242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2018-0433
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