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How Do the Accrual Pattern and Follow‐Up Duration Affect the Hazard Ratio Estimate When the Proportional Hazards Assumption Is Violated?

In randomized clinical trials, the magnitude of the treatment effect is often reported using the hazard ratio (HR) even when the proportional hazards (PH) assumption is not met. Conducting numerical studies, this commentary illustrates how/why the HR estimate via the standard Cox's procedure is...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Horiguchi, Miki, Hassett, Michael J., Uno, Hajime
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656438/
https://ncbi.nlm.nih.gov/pubmed/30201741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2018-0141
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