Rhodoquinone biosynthesis in C. elegans requires precursors generated by the kynurenine pathway

Parasitic helminths infect over a billion humans. To survive in the low oxygen environment of their hosts, these parasites use unusual anaerobic metabolism — this requires rhodoquinone (RQ), an electron carrier that is made by very few animal species. Crucially RQ is not made or used by any parasiti...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Del Borrello, Samantha, Lautens, Margot, Dolan, Kathleen, Tan, June H, Davie, Taylor, Schertzberg, Michael R, Spensley, Mark A, Caudy, Amy A, Fraser, Andrew G
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Biochemistry and Chemical Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656428/
https://ncbi.nlm.nih.gov/pubmed/31232688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48165
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