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Development of an in vitro media perfusion model of Leishmania major macrophage infection

BACKGROUND: In vitro assays are widely used in studies on pathogen infectivity, immune responses, drug and vaccine discovery. However, most in vitro assays display significant differences to the in vivo situation and limited predictive properties. We applied medium perfusion methods to mimic interst...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: O’Keeffe, Alec, Hyndman, Lauren, McGinty, Sean, Riezk, Alaa, Murdan, Sudaxshina, Croft, Simon L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656416/
https://ncbi.nlm.nih.gov/pubmed/31339931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219985
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