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Acute neurotoxicity following vincristine due to Charcot–Marie–Tooth disease in a young child with medulloblastoma

Vincristine (VCR), a microtubule inhibitor that arrests the cell cycle by blocking metaphase of mitosis, is unique among the vinca alkaloids for causing polyneuropathy. Patients with increased risk of VCR neurotoxicity include the elderly and those with prior history of neuropathy-prone medical cond...

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Pubblicato in:Neurooncol Pract
Autori principali: Kissoon, Trisha, Gururangan, Sridharan, Sladky, John
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656327/
https://ncbi.nlm.nih.gov/pubmed/31385990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nop/npz002
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