Selective Breeding for High Alcohol Consumption Enhances Response to Nicotine: Locomotor Activity, Dopamine in the Mesolimbic System, and Innate Genetic Differences

RATIONALE: There is evidence for a common genetic link between alcohol and nicotine dependence. Rodents selectively bred for high alcohol consumption/responsivity are also more likely to self-administer nicotine than controls. OBJECTIVES: The experiments examined the systemic response to nicotine, t...

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Pubblicato in:Psychopharmacology (Berl)
Autori principali: Deehan, Gerald A., Hauser, Sheketha R., Getachew, Bruk, Waeiss, R. Aaron, Engleman, Eric A., Knight, Christopher P., McBride, William J., Truitt, William A., Bell, Richard L., Rodd, Zachary A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6655552/
https://ncbi.nlm.nih.gov/pubmed/30043172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-018-4970-0
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