Transforming growth factor β(1) genotype and change in left ventricular mass during antihypertensive treatment–results from the swedish irbesartan left ventricular hypertrophy investigation versus atenolol (Silvhia)

Background: Angiotensin II, via the angiotensin II type 1 (AT1) receptor, may mediate myocardial fibrosis and myocyte hypertrophy seen in hypertensive left ventricular (LV) hypertrophy through production of transforming growth factor β(1)(TGF‐β(1)); AT1‐receptor antagonists reverse these changes. Th...

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Bibliografski detalji
Izdano u:Clin Cardiol
Glavni autori: Hallberg, Pär, Lind, Lars, Billberger, Katarina, Michaelsson, Karl, Karlsson, Julia, Kurland, Lisa, Kahan, Thomas, Malmqvist, Karin, Öhman, K. Peter, Nyström, Fredrik, Liljedahl, Ulrika, Syvänen, Ann‐Christine, Melhus, Håkan
Format: Artigo
Jezik:Inglês
Izdano: Wiley Periodicals, Inc. 2006
Teme:
Clinical Investigations
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6654118/
https://ncbi.nlm.nih.gov/pubmed/15049387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/clc.4960270315
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