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A microphysiological model of the bronchial airways reveals the interplay of mechanical and biochemical signals in bronchospasm

In asthma, airway smooth muscle (ASM) contraction and the subsequent decrease in airflow involve a poorly understood set of mechanical and biochemical events. Organ-level and molecular-scale models of the airway are frequently based on purely mechanical or biochemical considerations and do not accou...

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Vydáno v:Nat Biomed Eng
Hlavní autoři: Kilic, Onur, Yoon, Arum, Shah, Sagar R., Yong, Hwan Mee, Ruiz-Valls, Alejandro, Chang, Hao, Panettieri, Reynold A., Liggett, Stephen B., Quiñones-Hinojosa, Alfredo, An, Steven S., Levchenko, Andre
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6653686/
https://ncbi.nlm.nih.gov/pubmed/31150010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-019-0366-7
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