Cirsium japonicum var. maackii and apigenin block Hif‐2α‐induced osteoarthritic cartilage destruction

Although Hif‐2α is a master regulator of catabolic factor expression in osteoarthritis development, Hif‐2α inhibitors remain undeveloped. The aim of this study was to determine whether Cirsium japonicum var. maackii (CJM) extract and one of its constituents, apigenin, could attenuate the Hif‐2α‐indu...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Cho, Chanmi, Kang, Li‐Jung, Jang, Dain, Jeon, Jimin, Lee, Hyemi, Choi, Sangil, Han, Seong Jae, Oh, Eunjeong, Nam, Jiho, Kim, Chun Sung, Park, Eunkuk, Jeong, Seon‐Yong, Park, Chan Hum, Shin, Yu Su, Eyun, Seong‐il, Yang, Siyoung
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652892/
https://ncbi.nlm.nih.gov/pubmed/31148341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14418
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