Caspase-11 Contributes to Oviduct Pathology during Genital Chlamydia Infection in Mice

It has been shown that caspase-1, but not its upstream activator, ASC, contributes to oviduct pathology during mouse genital Chlamydia muridarum infection. We hypothesized that this dichotomy is due to the inadvertent absence of caspase-11 in previously used caspase-1-deficient mice. To address this...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Allen, John, Gyorke, Clare E., Tripathy, Manoj K., Zhang, Yugen, Lovett, Angela, Montgomery, Stephanie A., Nagarajan, Uma M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Host Response and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652777/
https://ncbi.nlm.nih.gov/pubmed/31160363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00262-19
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