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A Chemical Genetics Screen Reveals Influence of p38 Mitogen-Activated Protein Kinase and Autophagy on Phagosome Development and Intracellular Replication of Brucella neotomae in Macrophages

Brucella is an intracellular bacterial pathogen that causes chronic systemic infection in domesticated livestock and poses a zoonotic infectious risk to humans. The virulence of Brucella is critically dependent on its ability to replicate and survive within host macrophages. Brucella modulates host...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Kang, Yoon-Suk, Kirby, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652748/
https://ncbi.nlm.nih.gov/pubmed/31160361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00044-19
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