An RNAi screen in human cell lines reveals conserved DNA damage repair pathways that mitigate formaldehyde sensitivity

Formaldehyde is a ubiquitous DNA damaging agent, with human exposures occurring from both exogenous and endogenous sources. Formaldehyde exposure can result in multiple types of DNA damage, including DNA-protein crosslinks and thus, is representative of other exposures that induce DNA-protein crossl...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Juarez, Eleonora, Chambwe, Nyasha, Tang, Weiliang, Mitchell, Asia D., Owen, Nichole, Kumari, Anuradha, Monnat, Raymond J., McCullough, Amanda K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652219/
https://ncbi.nlm.nih.gov/pubmed/30389308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2018.10.002
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