Transcription Factor IRF4 Dysfunction Affects the Immunosuppressive Function of Treg Cells in Patients with Primary Immune Thrombocytopenia

BACKGROUND: Th17/Treg balance skews towards Th17 in ITP patient. IRF4 has been highlighted for its close relationship to the immunosuppressive function of Treg cells and the IL-17 synthesis in CD4(+) T cells. This study was aimed at examining the effects of IRF4 to the Th17/Treg cells in patients wi...

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Bibliografiske detaljer
Udgivet i:Biomed Res Int
Main Authors: Tang, Meiwen, Cheng, Luya, Li, Feng, Wu, Boting, Chen, Pu, Zhan, Yanxia, Hua, Fanli, Min, Zhihui, Ke, Yang, Liu, Chanjuan, Yuan, Ling, Sun, Lihua, Chen, Hao, Ji, Lili, Cheng, Yunfeng
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6652070/
https://ncbi.nlm.nih.gov/pubmed/31380412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/1050285
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