A single-arm pilot study of metformin in patients with autosomal dominant polycystic kidney disease

BACKGROUND: Metformin has shown promising results regarding cystogenesis inhibition in preclinical studies with autosomal dominant polycystic kidney disease (ADPKD) models. We designed a prospective, preliminary, single-arm study to evaluate the tolerability, safety and the effect of Metformin on ki...

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Vydáno v:BMC Nephrol
Hlavní autoři: Sorohan, Bogdan Marian, Ismail, Gener, Andronesi, Andreea, Micu, Georgia, Obrișcă, Bogdan, Jurubiță, Roxana, Sinescu, Ioanel, Baston, Cătălin
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651959/
https://ncbi.nlm.nih.gov/pubmed/31337351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-019-1463-2
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