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2-Carba cyclic phosphatidic acid inhibits lipopolysaccharide-induced prostaglandin E2 production in a human macrophage cell line

Cyclic phosphatidic acid (cPA) is a naturally occurring phospholipid mediator that contains a unique cyclic phosphate ring at the sn-2 and sn-3 positions of its glycerol backbone. Using mouse models for multiple sclerosis (cuprizone-induced demyelination and experimental autoimmune encephalomyelitis...

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Bibliographic Details
Published in:Biochem Biophys Rep
Main Authors: Shibaike, Yuki, Gotoh, Mari, Ogawa, Chinatsu, Nakajima, Shingo, Yoshikawa, Keisuke, Kobayashi, Tetsuyuki, Murakami-Murofushi, Kimiko
Format: Artigo
Language:Inglês
Published: Elsevier 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651843/
https://ncbi.nlm.nih.gov/pubmed/31367683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2019.100668
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