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5-Amino-1-β-D-Ribofuranosyl-Imidazole-4-Carboxamide (AICAR) Reduces Peripheral Inflammation by Macrophage Phenotype Shift

The stimulation of the AMP-activated kinase (AMPK) by 5-amino-1-β-D-ribofuranosyl-imidazole-4-carboxamide (AICAR) has been associated with antihyperalgesia and the inhibition of nociceptive signaling in the spinal cord in models of paw inflammation. The attenuated nociception comes along with a stro...

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Foilsithe in:Int J Mol Sci
Main Authors: Martin, Lisa Maria, Möller, Moritz, Weiss, Ulrike, Russe, Otto Quintus, Scholich, Klaus, Pierre, Sandra, Geisslinger, Gerd, Niederberger, Ellen
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651813/
https://ncbi.nlm.nih.gov/pubmed/31269729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20133255
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