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Fine-Tuning the Activation Mode of an 1,3-Indandione-Based Ruthenium(II)-Cymene Half-Sandwich Complex by Variation of Its Leaving Group

Fine-tuning of the properties of a recently reported 1,3-indandione-based organoruthenium complex is attempted to optimize the stability under physiological conditions. Previous work has shown its capacity of inhibiting topoisomerase IIα; however, fast aquation leads to undesired reactions and ligan...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Mokesch, Stephan, Schwarz, Daniela, Hejl, Michaela, Klose, Matthias H. M., Roller, Alexander, Jakupec, Michael A., Kandioller, Wolfgang, Keppler, Bernhard K.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651387/
https://ncbi.nlm.nih.gov/pubmed/31252521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24132373
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