Quantitative Mass Spectrometry Imaging Reveals Mutation Status-independent Lack of Imatinib in Liver Metastases of Gastrointestinal Stromal Tumors

Mass spectrometry imaging (MSI) is an enabling technology for label-free drug disposition studies at high spatial resolution in life science- and pharmaceutical research. We present the first extensive clinical matrix-assisted laser desorption/ionization (MALDI) quantitative mass spectrometry imagin...

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Pubblicato in:Sci Rep
Autori principali: Abu Sammour, Denis, Marsching, Christian, Geisel, Alexander, Erich, Katrin, Schulz, Sandra, Ramallo Guevara, Carina, Rabe, Jan-Hinrich, Marx, Alexander, Findeisen, Peter, Hohenberger, Peter, Hopf, Carsten
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650609/
https://ncbi.nlm.nih.gov/pubmed/31337874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47089-5
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