The Interaction of Klebsiella pneumoniae With Lipid Rafts-Associated Cholesterol Increases Macrophage-Mediated Phagocytosis Due to Down Regulation of the Capsule Polysaccharide

Klebsiella pneumoniae successfully colonizes host tissues by recognizing and interacting with cholesterol present on membrane-associated lipid rafts. In this study, we evaluated the role of cholesterol in the expression of capsule polysaccharide genes of K. pneumoniae and its implication in resistan...

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Detalhes bibliográficos
Publicado no:Front Cell Infect Microbiol
Main Authors: Ares, Miguel A., Sansabas, Alejandro, Rodríguez-Valverde, Diana, Siqueiros-Cendón, Tania, Rascón-Cruz, Quintín, Rosales-Reyes, Roberto, Jarillo-Quijada, Ma. Dolores, Alcántar-Curiel, María D., Cedillo, María L., Torres, Javier, Girón, Jorge A., De la Cruz, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Cellular and Infection Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650577/
https://ncbi.nlm.nih.gov/pubmed/31380298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00255
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