Stable Occupancy of the Crimean-Congo Hemorrhagic Fever Virus-Encoded Deubiquitinase Blocks Viral Infection

Crimean-Congo hemorrhagic fever virus (CCHFV) infection can result in a severe hemorrhagic syndrome for which there are no antiviral interventions available to date. Certain RNA viruses, such as CCHFV, encode cysteine proteases of the ovarian tumor (OTU) family that antagonize interferon (IFN) produ...

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Udgivet i:mBio
Main Authors: Scholte, Florine E. M., Hua, Brian L., Spengler, Jessica R., Dzimianski, John V., Coleman-McCray, JoAnn D., Welch, Stephen R., McMullan, Laura K., Nichol, Stuart T., Pegan, Scott D., Spiropoulou, Christina F., Bergeron, Éric
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650548/
https://ncbi.nlm.nih.gov/pubmed/31337717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01065-19
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