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Apelin affects the mouse aging urinary peptidome with minimal effects on kidney

Kidney function is altered by age together with a declined filtration capacity of 5–10% per decade after 35 years. Renal aging shares many characteristics with chronic kidney disease. Plasma levels of the bioactive peptide apelin also decline with age and apelin has been shown to be protective in ch...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Vinel, Claire, Schanstra, Joost P., Boizard, Franck, Péreira, Ophélie, Auriau, Johanna, Dortignac, Alizée, Breuil, Benjamin, Feuillet, Guylène, Nkuipou-Kenfack, Esther, Zürbig, Petra, Valet, Philippe, Bascands, Jean-Loup, Dray, Cédric, Denis, Colette
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650410/
https://ncbi.nlm.nih.gov/pubmed/31337837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47109-4
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