A Dual-Responsive Probe for Detecting Cellular Hypoxia using (19)F Magnetic Resonance and Fluorescence

We report the first dual-responsive (19)F MRI and fluorescence imaging probe for cellular hypoxia. The Cu(2+)-based probe exhibits no (19)F MR signal and reduced fluorescence signal due to paramagnetic quenching; however, the probe turns-on in both modes following reduction to Cu(+). This bimodal ag...

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Udgivet i:Chem Commun (Camb)
Main Authors: Kadakia, Rahul T., Xie, Da, Martinez, Daniel, Yu, Meng, Que, Emily L.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6650319/
https://ncbi.nlm.nih.gov/pubmed/31219109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9cc00375d
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