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DNA-segment-capture model for loop extrusion by structural maintenance of chromosome (SMC) protein complexes

Cells possess remarkable control of the folding and entanglement topology of long and flexible chromosomal DNA molecules. It is thought that structural maintenance of chromosome (SMC) protein complexes play a crucial role in this, by organizing long DNAs into series of loops. Experimental data sugge...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Marko, John F, De Los Rios, Paolo, Barducci, Alessandro, Gruber, Stephan
Format: Artigo
Language:Inglês
Published: Oxford University Press 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649773/
https://ncbi.nlm.nih.gov/pubmed/31175837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz497
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