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Insights into BRCA Cancer Predisposition from Integrated Germline and Somatic Analyses in 7632 Cancers
BACKGROUND: It is often assumed any cancer in a germline BRCA1 or BRCA2 (collectively termed BRCA) mutation carrier was caused by that mutation. It is also often assumed the occurrence of breast or ovarian cancer in an individual with a variant of uncertain significance (VUS) suggests the VUS is pat...
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| Publicado no: | JNCI Cancer Spectr |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6649772/ https://ncbi.nlm.nih.gov/pubmed/31360904 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jncics/pkz028 |
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