Rational design of an XNA ligase through docking of unbound nucleic acids to toroidal proteins

Xenobiotic nucleic acids (XNA) are nucleic acid analogues not present in nature that can be used for the storage of genetic information. In vivo XNA applications could be developed into novel biocontainment strategies, but are currently limited by the challenge of developing XNA processing enzymes s...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Vanmeert, Michiel, Razzokov, Jamoliddin, Mirza, Muhammad Usman, Weeks, Stephen D, Schepers, Guy, Bogaerts, Annemie, Rozenski, Jef, Froeyen, Mathy, Herdewijn, Piet, Pinheiro, Vitor B, Lescrinier, Eveline
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2019
Konular:
Synthetic Biology and Bioengineering
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649754/
https://ncbi.nlm.nih.gov/pubmed/31334814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz551
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