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Effective Estimation of Ligand-Binding Affinity Using Biased Sampling Method

[Image: see text] The binding between two biomolecules is one of the most critical factors controlling many bioprocesses. Therefore, it is of great interest to derive a reliable method to calculate the free binding energy between two biomolecules. In this work, we have demonstrated that the binding...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Ngo, Son Tung, Vu, Khanh B., Bui, Le Minh, Vu, Van V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648447/
https://ncbi.nlm.nih.gov/pubmed/31459599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b03258
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