Thiophene Derivatives as New Anticancer Agents and Their Therapeutic Delivery Using Folate Receptor-Targeting Nanocarriers

[Image: see text] A series of thiophene derivatives were synthesized by functionalization of 2,3-fused thiophene scaffolds. Their cytotoxicity was assessed against HeLa and Hep G2 cells. Compound 480 was identified as a promising candidate because of its low IC(50) in HeLa (12.61 μg/mL) and Hep G2 (...

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Bibliografiset tiedot
Julkaisussa:ACS Omega
Päätekijät: Zhao, Menghui, Cui, Yaxin, Zhao, Lang, Zhu, Tianyu, Lee, Robert J., Liao, Weiwei, Sun, Fengying, Li, Youxin, Teng, Lesheng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Chemical Society 2019
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648408/
https://ncbi.nlm.nih.gov/pubmed/31459975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b00554
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