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4,6-Dihydroxysalicylic Acid-Catalyzed Oxidative Condensation of Benzylic Amines and Aromatic Ketones for the Preparation of 2,4,6-Trisubstituted Pyridines and Its Application to Metal-Free Synthesis of G-Quadruplex Binding Ligands
[Image: see text] 4,6-Dihydroxysalicylic acid was activated under air to catalyze the one-pot oxidative condensation reaction of benzylamines with acetophenones in the presence of BF(3)·Et(2)O, affording 2,4,6-trisubstituted pyridines in yields of 59–91%. During this metal-free oxidative condensatio...
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| Vydáno v: | ACS Omega |
|---|---|
| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Chemical Society
2019
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6648211/ https://ncbi.nlm.nih.gov/pubmed/31459991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b00999 |
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