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Reactions of Piperazin-2-one, Morpholin-3-one, and Thiomorpholin-3-one with Triethyl Phosphite Prompted by Phosphoryl Chloride: Scope and Limitations

[Image: see text] The reaction of the title lactams with triethyl phosphite prompted by phosphoryl chloride provided six-membered ring heterocyclic phosphonates or bisphosphonates. These novel scaffolds might be of interest as building blocks in medicinal chemistry. The course of the reaction was de...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Argüello-Velasco, Rubén Oswaldo, Dziuk, Błażej, Zarychta, Bartosz, Ordóñez, Mario, Kafarski, Paweł
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648091/
https://ncbi.nlm.nih.gov/pubmed/31459993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b01137
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