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Metabolites of Vinca Alkaloid Vinblastine: Tubulin Binding and Activation of Nausea-Associated Receptors
[Image: see text] Vinblastine (VLB) is an antimitotic drug that binds to the vinca site of tubulin. The molecule possesses a high molecular weight and a complex chemical structure with many possibilities of metabolization. Despite advances in drug discovery research in reducing drug toxicity, the ca...
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| Publicat a: | ACS Omega |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Chemical Society
2019
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6648052/ https://ncbi.nlm.nih.gov/pubmed/31460070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b00652 |
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