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Reducing the Amyloidogenicity of Functional Amyloid Protein FapC Increases Its Ability To Inhibit α-Synuclein Fibrillation

[Image: see text] Functional amyloid (FA) proteins have evolved to assemble into fibrils with a characteristic cross-β structure, which stabilizes biofilms and contributes to bacterial virulence. Some of the most studied bacterial FAs are the curli protein CsgA, expressed in a wide range of bacteria...

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Bibliografiske detaljer
Udgivet i:ACS Omega
Main Authors: Christensen, Line Friis Bakmann, Jensen, Kirstine Friis, Nielsen, Janni, Vad, Brian Stougaard, Christiansen, Gunna, Otzen, Daniel Erik
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2019
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6647998/
https://ncbi.nlm.nih.gov/pubmed/31459612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b03590
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