Acetylated Benzothiazolone as Homobivalent SPECT Metallo-Radiopharmaceutical (99m)Tc-(6-AcBTZ)(2)DTPA: Design, Synthesis, and Preclinical Evaluation for Mapping 5-HT(1A/7) Receptors

[Image: see text] Mapping different structural forms of serotonin subtypes 5-HT(1A)–5-HT(7) using a selective-specific ligand with good pharmacokinetics and brain permeability can open avenues for personalized medication in depressed population. Herein, the selective 5-HT(1A/7) antagonist, modified...

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Vydáno v:ACS Omega
Hlavní autoři: Jha, Preeti, Chaturvedi, Shubhra, Anju, Kaul, Ankur, Jain, Nidhi, Mishra, Anil K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2019
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6647941/
https://ncbi.nlm.nih.gov/pubmed/31460097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b00633
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