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Effect of a Vasopressin V2 Receptor Antagonist on Polycystic Kidney Disease Development in a Rat Model

BACKGROUND: Vasopressin V2 receptor inhibition is a clinically validated mechanism of action in the treatment of autosomal dominant polycystic kidney disease (ADPKD). In this study, the effect of lixivaptan, a potent, selective vasopressin V2 antagonist, was evaluated in PCK rats, a validated animal...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Nephrol
Egile Nagusiak: Wang, Xiaofang, Constans, Megan M., Chebib, Fouad T., Torres, Vicente E., Pellegrini, Lorenzo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6647848/
https://ncbi.nlm.nih.gov/pubmed/31117065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000500667
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