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The Alu neurodegeneration hypothesis: A primate-specific mechanism for neuronal transcription noise, mitochondrial dysfunction, and manifestation of neurodegenerative disease
It is hypothesized that retrotransposons have played a fundamental role in primate evolution and that enhanced neurologic retrotransposon activity in humans may underlie the origin of higher cognitive function. As a potential consequence of this enhanced activity, it is likely that neurons are susce...
Shranjeno v:
| izdano v: | Alzheimers Dement |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6647845/ https://ncbi.nlm.nih.gov/pubmed/28242298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2017.01.017 |
| Oznake: |
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