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Genome editing of human pancreatic beta cell models: problems, possibilities and outlook

Understanding the molecular mechanisms behind beta cell dysfunction is essential for the development of effective and specific approaches for diabetes care and prevention. Physiological human beta cell models are needed for this work. We review the possibilities and limitations of currently availabl...

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Detalhes bibliográficos
Publicado no:Diabetologia
Main Authors: Balboa, Diego, Prasad, Rashmi B., Groop, Leif, Otonkoski, Timo
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6647170/
https://ncbi.nlm.nih.gov/pubmed/31161346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-019-4908-z
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