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Concise Review: Application of Chemically Modified mRNA in Cell Fate Conversion and Tissue Engineering

Chemically modified RNA (cmRNA) has potential as a safe and efficient tool for nucleic acid‐based therapies and regenerative medicine. Modifications in the chemistry of mRNA can enhance stability, reduce immunogenicity, and thus facilitate mRNA‐based nucleic acid therapy, which eliminates risk of in...

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Vydáno v:Stem Cells Transl Med
Hlavní autoři: Badieyan, Zohreh Sadat, Evans, Todd
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley & Sons, Inc. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6646692/
https://ncbi.nlm.nih.gov/pubmed/30891922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.18-0259
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