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Vps10-mediated targeting of Pep4 determines the activity of the vacuole in a substrate-dependent manner

The vacuole is the hydrolytic compartment of yeast cells and has a similar function as the lysosome of higher eukaryotes in detoxification and recycling of macromolecules. We analysed the contribution of single vacuolar enzymes to pexophagy and identified the phospholipase Atg15, the V-ATPase factor...

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Publicado en:Sci Rep
Main Authors: Boutouja, Fahd, Stiehm, Christian M., Mastalski, Thomas, Brinkmeier, Rebecca, Reidick, Christina, El Magraoui, Fouzi, Platta, Harald W.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6646403/
https://ncbi.nlm.nih.gov/pubmed/31332264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-47184-7
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