Determining Possible Shared Genetic Architecture Between Myopia and Primary Open-Angle Glaucoma

PURPOSE: To determine genetic correlations between common myopia and primary open-angle glaucoma (POAG). METHODS: We tested the association of myopia polygenic risk scores (PRSs) with POAG and POAG endophenotypes using two studies: the Australian & New Zealand Registry of Advanced Glaucoma (ANZR...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Iglesias, Adriana I., Ong, Jue Sheng, Khawaja, Anthony P., Gharahkhani, Puya, Tedja, Milly S., Verhoeven, Virginie J. M., Bonnemaijer, Pieter W. M., Wolfs, Roger C. W., Young, Terri L., Jansonius, Nomdo M., Craig, Jamie E., Stambolian, Dwight, van Duijn, Cornelia M., MacGregor, Stuart, Klaver, Caroline C. W.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2019
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6645704/
https://ncbi.nlm.nih.gov/pubmed/31323684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-26231
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