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Roles of Active-Site Aromatic Residues in Cold Adaptation of Sphingomonas glacialis Esterase EstSP1

[Image: see text] The aromatic amino acids, Tyr or Trp, which line the active-site walls of esterases, stabilize the catalytic His loop via hydrogen bonding. A Tyr residue is preferred in extremophilic esterases (psychrophilic or hyperthermophilic esterases), whereas a Trp residue is preferred in mo...

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Detalhes bibliográficos
Publicado no:ACS Omega
Main Authors: Kashif, Ayesha, Tran, Lan-Huong, Jang, Sei-Heon, Lee, ChangWoo
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6645578/
https://ncbi.nlm.nih.gov/pubmed/31457406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01435
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