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Therapeutic strategies for sickle cell disease: towards a multi-agent approach
For over 100 years, clinicians and scientists have been unraveling the consequences of the A to T substitution in the beta globin gene that produces hemoglobin S, which leads to the systemic manifestations of sickle cell disease (SCD), including vaso-occlusion, anemia, hemolysis, organ injury and pa...
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| Опубликовано в: : | Nat Rev Drug Discov |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6645400/ https://ncbi.nlm.nih.gov/pubmed/30514970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41573-018-0003-2 |
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