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Atom-Economical and Metal-Free Synthesis of Multisubstituted Furans from Intramolecular Aziridine Ring Opening

[Image: see text] Multisubstituted furans were prepared from dialkyl 2-(aziridin-2-ylmethylene)malonate and/or 1,3-dione through aziridine ring opening by the internal carbonyl oxygen with the assistance of BF(3)·OEt(2), followed by aromatization. This synthetic method is free from any metal and is...

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Pubblicato in:ACS Omega
Autori principali: Yadav, Nagendra Nath, Jeong, Hyeonsu, Ha, Hyun-Joon
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2017
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6645301/
https://ncbi.nlm.nih.gov/pubmed/31457314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01542
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