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Circular Dichroistic Impacts of 1-(3-Dimethylaminopropyl)-3-ethylurea: Secondary Structure Artifacts Arising from Bioconjugation Using 1-Ethyl-3-[3-dimethylaminopropyl]carbodiimide
[Image: see text] 1-Ethyl-3-[3-dimethylaminopropyl]carbodiimide (EDC) is a commonly used reagent for bioconjugation and peptide synthesis. Both EDC and the corresponding urea derivative, 1-(3-dimethylaminopropyl)-3-ethylurea (EDU), are achiral. As the reagent is active in aqueous solutions, it is a...
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| I publikationen: | ACS Omega |
|---|---|
| Huvudupphovsmän: | , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Chemical Society
2017
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6645161/ https://ncbi.nlm.nih.gov/pubmed/31457370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b01288 |
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