The Inflammasome Adaptor ASC Intrinsically Limits CD4(+) T-Cell Proliferation to Help Maintain Intestinal Homeostasis

The inflammasome is a multi-protein complex that mediates proteolytic cleavage and release of the pro-inflammatory cytokines IL-1β and IL-18, and pyroptosis—a form of cell death induced by various pathogenic bacteria. Apoptosis-associated speck-like protein containing a CARD (ASC) has a pivotal role...

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Pubblicato in:Front Immunol
Autori principali: Javanmard Khameneh, Hanif, Leong, Keith Weng Kit, Mencarelli, Andrea, Vacca, Maurizio, Mambwe, Bezaleel, Neo, Kurt, Tay, Alice, Zolezzi, Francesca, Lee, Bernett, Mortellaro, Alessandra
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6644529/
https://ncbi.nlm.nih.gov/pubmed/31379813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01566
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