Environmentally Benign and Facile Process for the Synthesis of Pantoprazole Sodium Sesquihydrate: Phase Transformation of Pantoprazole Sodium Heterosolvate to Pantoprazole Sodium Sesquihydrate

[Image: see text] A cost-effective, scalable, and environmentally benign process is herein reported for the synthesis of pantoprazole sodium sesquihydrate: 5-(difluromethoxy)-2-[{(3,4-dimethoxy-2-pyridinyl)methyl}sulfinyl]-1H-benzimidazole sodium sesquihydrate. At least two of the three main synthet...

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Publicat a:ACS Omega
Autors principals: Awasthi, Arun Kumar, Kumar, Lalit, Tripathi, Punit, Golla, Madhava, Aga, Mushtaq A., Reddy, Cirandur Suresh, Kumar, Pramod
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2017
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6644499/
https://ncbi.nlm.nih.gov/pubmed/31457814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.7b00743
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