Genome‐wide meta‐analysis identifies 3 novel loci associated with stroke

We conducted a European‐only and transancestral genome‐wide association meta‐analysis in 72,147 stroke patients and 823,869 controls using data from UK Biobank (UKB) and the MEGASTROKE consortium. We identified an exonic polymorphism in NOS3 (rs1799983, p.Glu298Asp; p = 2.2E‐8, odds ratio [OR] = 1.0...

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Detalles Bibliográficos
Publicado en:Ann Neurol
Autores principales: Malik, Rainer, Rannikmäe, Kristiina, Traylor, Matthew, Georgakis, Marios K., Sargurupremraj, Muralidharan, Markus, Hugh S., Hopewell, Jemma C., Debette, Stephanie, Sudlow, Cathie L. M., Dichgans, Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Brief Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6644297/
https://ncbi.nlm.nih.gov/pubmed/30383316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25369
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