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Cryptolepine, the Main Alkaloid of the Antimalarial Cryptolepis sanguinolenta (Lindl.) Schlechter, Induces Malformations in Zebrafish Embryos

BACKGROUND: Previous studies on cryptolepine, the antimalarial and cytotoxic alkaloid of Cryptolepis sanguinolenta, showed that it preferentially accumulates in rapidly proliferating cells and melanin-containing tissues. Subsequently, we demonstrated that cryptolepine was toxic to murine embryos in...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biochem Res Int
Main Authors: Mensah, Kwesi Boadu, Benneh, Charles, Forkuo, Arnold Donkor, Ansah, Charles
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6644280/
https://ncbi.nlm.nih.gov/pubmed/31360547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/7076986
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