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Restriction of Cellular Plasticity of Differentiated Cells Mediated by Chromatin Modifiers, Transcription Factors and Protein Kinases

Ectopic expression of master regulatory transcription factors can reprogram the identity of specific cell types. The effectiveness of such induced cellular reprogramming is generally greatly reduced if the cellular substrates are fully differentiated cells. For example, in the nematode C. elegans, t...

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Detalles Bibliográficos
Publicado en:G3 (Bethesda)
Main Authors: Rahe, Dylan P., Hobert, Oliver
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643894/
https://ncbi.nlm.nih.gov/pubmed/31088904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.119.400328
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