Employing Macrophage-Derived Microvesicle for Kidney-Targeted Delivery of Dexamethasone: An Efficient Therapeutic Strategy against Renal Inflammation and Fibrosis

Although glucocorticoids are the mainstays in the treatment of renal diseases for decades, the dose dependent side effects have largely restricted their clinical use. Microvesicles (MVs) are small lipid-based membrane-bound particles generated by virtually all cells. Here we show that RAW 264.7 macr...

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Udgivet i:Theranostics
Main Authors: Tang, Tao-Tao, Lv, Lin-Li, Wang, Bin, Cao, Jing-Yuan, Feng, Ye, Li, Zuo-Lin, Wu, Min, Wang, Feng-Mei, Wen, Yi, Zhou, Le-Ting, Ni, Hai-Feng, Chen, Ping-Sheng, Gu, Ning, Crowley, Steven D., Liu, Bi-Cheng
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2019
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643445/
https://ncbi.nlm.nih.gov/pubmed/31367254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.33520
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