Employing Macrophage-Derived Microvesicle for Kidney-Targeted Delivery of Dexamethasone: An Efficient Therapeutic Strategy against Renal Inflammation and Fibrosis

Although glucocorticoids are the mainstays in the treatment of renal diseases for decades, the dose dependent side effects have largely restricted their clinical use. Microvesicles (MVs) are small lipid-based membrane-bound particles generated by virtually all cells. Here we show that RAW 264.7 macr...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Tang, Tao-Tao, Lv, Lin-Li, Wang, Bin, Cao, Jing-Yuan, Feng, Ye, Li, Zuo-Lin, Wu, Min, Wang, Feng-Mei, Wen, Yi, Zhou, Le-Ting, Ni, Hai-Feng, Chen, Ping-Sheng, Gu, Ning, Crowley, Steven D., Liu, Bi-Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643445/
https://ncbi.nlm.nih.gov/pubmed/31367254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.33520
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