Lipidomics reveal aryl hydrocarbon receptor (Ahr)-regulated lipid metabolic pathway in alpha-naphthyl isothiocyanate (ANIT)-induced intrahepatic cholestasis

1. Ultra-performance liquid chromatography coupled with electrospray ionization quadrupole mass spectrometry (UPLC-ESI-QTOF MS)-based lipidomics was employed to elucidate new mechanism of alpha-naphthyl isothiocyanate (ANIT)-induced intrahepatic cholestasis in mice. 2. Multiple lipid components sign...

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Gepubliceerd in:Xenobiotica
Hoofdauteurs: Wang, Bao-Long, Zhang, Chang-Wen, Wang, Liang, Tang, Kun-Long, Tanaka, Naoki, Gonzalez, Frank J., Xu, Yong, Fang, Zhong-Ze
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643298/
https://ncbi.nlm.nih.gov/pubmed/29737914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00498254.2018.1467065
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