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Film Interface for Drug Testing for Delivery to Cells in Culture and in the Brain

Brain access remains a major challenge in drug testing. The nearly ‘impermeable’ blood-brain-barrier (BBB) prevents most drugs from gaining access to brain cells via systematic intravenous (IV) injection. In this study, silk fibroin films were used as drug carrier as well as cell culture substrate t...

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Detalhes bibliográficos
Publicado no:Acta Biomater
Main Authors: Tang-Schomer, Min D., Kaplan, David L., Whalen, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642835/
https://ncbi.nlm.nih.gov/pubmed/30836199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2019.02.052
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